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What is Colchicine?

Colchicine, also known as Colcrys is primarily used to prevent gout attacks such as sudden, severe pain in joints. Colchicine can be also used as pain relief when gout attacks do occur. Colchicine can also be used to treat familial Mediterranean fever (FMF). Colcrys in itself isn’t a pain reliever and can’t be used to treat pain caused sources other than gout or FMF.

Always read the patient information and instructions carefully before using this medication.

• Take colchicine 0.6mg orally as prescribed by your doctor. This medication can be taken with or without food.
• Do not alter or change your colchicine dosage. Taking more than your recommended dose may not increase its effectiveness but could increase the likelihood of side effects.
• When treating gout, Colcrys is most effective when taken at the first sign of an attack. The recommended dose to treat an attack is 1.2mg followed by 0.6 an hour later. Do not take more than 1.8mg in an hour period.
• When treating FMF, a normal dose is between 1.2mg and 2.4mg each day. This can be taken in either one or two doses. Always follow your doctor’s instructions.
• Avoid grapefruit , grapefruit juice and alcohol while taking this medication.

Make sure to tell your doctor and pharmacist:

• If you have any drug allergies.
• Which other prescription and non-prescription medications you currently take.
• Your medical history, especially if you have ever had kidney or liver problems.
• If you are breast feeding as this medication passes into breast milk.

Also be aware that:

• Taking colchicine and alcohol can decrease its effectiveness. Limit your alcohol intake while taking this medicine.
• You should avoid grapefruit and grapefruit juice while taking Colcrys.
• This medication may affect your bodies effectiveness to absorb some foods and nutrients.
• Older adults may be more sensitive to the side effects of colchicine.
• Only take this medication when needed during pregnancy.
• Colchicine can decrease your sperm production which can affect men’s ability to father a child.

Common colchicine side effects may include but are not limited to:

• Stomach pain.
• Nausea, vomiting or diarrhea.

Contact your doctor if you experience any of the following side effects of colchicine:

• Muscle pain or weakness.
• Easy or unusual bleeding or bruising.
• Feeling weak or tired.
• A numbness or tingling feeling in fingers or toes.
• Severe or ongoing vomiting or diarrhea.
• Pale or gray appearance of your lips, tongue, or hands.
• Flu symptoms such as fever, chills or body aches.

Q: What is the maximum dose of colchicine?

A: The maximum recommended dose of colchicine is 1.8 milligrams taken over a 1-hour period. Ask your doctor how long to wait before retaking this medication.

Q: What should I avoid while taking colchicine?

A: You should avoid grapefruit, grapefruit juice and alcohol while taking this medication.